Methadone Analgesia in Cancer Pain Patients on Chronic Methadone Maintenance Therapy
نویسندگان
چکیده
منابع مشابه
Relationship between serum methadone concentration and cold pressor pain sensitivity in patients undergoing methadone maintenance therapy
Hyperalgesia is a common clinical phenomenon among opioid dependent patients on methadone maintenance therapy (MMT) and it may be associated with undertreated pain and/or therapeutic failure. This study aimed to investigate association between serum methadone concentration (SMC) and cold pressor pain responses. Cold pressor pain responses in 147 opioid dependent patients on MMT were assessed us...
متن کاملRelationship between serum methadone concentration and cold pressor pain sensitivity in patients undergoing methadone maintenance therapy
Hyperalgesia is a common clinical phenomenon among opioid dependent patients on methadone maintenance therapy (MMT) and it may be associated with undertreated pain and/or therapeutic failure. This study aimed to investigate association between serum methadone concentration (SMC) and cold pressor pain responses. Cold pressor pain responses in 147 opioid dependent patients on MMT were assessed us...
متن کاملConcomitant Drug Use in Patients on Methadone Maintenance Therapy
Background: Methadone maintenance therapy (MMT) is considered as an efficient and effective treatment in management of high risk opioids addiction; although, concomitant use of other drugs may interfere with treatment course and outcome in MMT cases. This study aimed at evaluating patterns of drug use along with methadone based on self reported and urine analysis data in two MMT clinics. Method...
متن کاملInfluence of methadone on clopidogrel in addicts on methadone maintenance therapy
Background: Clopidogrel is a prodrug that converts in the liver to an active thiol metabolite, which irreversibly inhibits the platelet P2Y12 adenosine diphosphate receptor. It seems that methadone as CYP2C19 inhibitor affects ticlopidine activity in vivo. This study aimed to test the ability of methadone in changing ticlopidine pharmacokinetics. Methods: We conducted a case–control st...
متن کاملDose-Dependent Effects of Methadone on QT interval in Patients under Methadone Maintenance Treatment
Background: The role of methadone in QTc prolongation, Torsades de Pointes (TdP) arrhythmia and sudden cardiac death has been debated. Because of widespread use of methadone in methadone maintenance treatment (MMT) centers, we aimed to study dose-related effects of methadone on QTc prolongation. Methods: In a comparative observational study, 90 patients who were under MMT were evaluated. Patien...
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ژورنال
عنوان ژورنال: Journal of Pain and Symptom Management
سال: 2001
ISSN: 0885-3924
DOI: 10.1016/s0885-3924(00)00252-9